Epidermal Growth Factor Signaling and Mitogenesis in Plcg1 Null Mouse Embryonic Fibroblasts

Gene targeting techniques and early mouse embryos have been used to produce immortalized fibroblasts genetically deficient in phospholipase C (PLC)-γ1, a ubiquitous tyrosine kinase substrate. Plcg1(−/−) embryos die at embryonic day 9; however, cells derived from these embryos proliferate as well as...

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Detalles Bibliográficos

Publicado en:	Mol Biol Cell
Principais autores:	Ji, Qun-sheng, Ermini, Sandra, Baulida, Josep, Sun, Feng-lei, Carpenter, Graham
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Cell Biology 1998
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529375/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.4.749
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