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Total Synthesis of (±)-Symbioimine

[Image: see text] The synthesis of (±)-symbioimine (1) has been completed in only 12 linear steps in 8% overall yield. The key step is the treatment of 13b with BF(3)•Et(2)O to generate N-carboalkoxydihydropyridinium cation 14b, which undergoes a novel sterospecific intramolecular Diels-Alder reacti...

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Autors principals: Zou, Yefen, Che, Qinglin, Snider, Barry B.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529459/
https://ncbi.nlm.nih.gov/pubmed/17107083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062333s
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