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The Catalytic Power of Uracil DNA Glycosylase in the Opening of Thymine Base Pairs

Uracil DNA glycosylase (UNG) locates uracil and its structural congener thymine in the context of duplex DNA using a base flipping mechanism. NMR imino proton exchange measurements were performed on free and UNG-bound DNA duplexes in which a single thymine (T) was paired with a series of adenine ana...

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Detalhes bibliográficos
Main Authors: Cao, Chunyang, Jiang, Yu Lin, Krosky, Daniel J., Stivers, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529456/
https://ncbi.nlm.nih.gov/pubmed/17017766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062978n
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