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Replication and transformation functions of in vitro-generated simian virus 40 large T antigen mutants.

We used sodium bisulfite mutagenesis to introduce point mutations within the early region of the simian virus 40 genome. Seventeen mutants which contained amino acid changes in the amino-terminal half of the large T antigen coding sequence were assayed for their ability to replicate viral DNA and to...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Rutila, J E, Imperiale, M J, Brockman, W W
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3009866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.58.2.526-535.1986
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