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Mutant of simian virus 40 large T-antigen that is defective for viral DNA synthesis, but competent for transformation of cultured rat cells.

A mutant was isolated which demonstrates that the transforming activity of simian virus 40 large T-antigen is separable from its function in viral DNA replication. The mutant, SVR9D, is nonconditionally defective for viral DNA synthesis, but competent at wild-type level for morphological transformat...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsman: Stringer, J R
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 1982
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6285001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.42.3.854-864.1982
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