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Replication and transformation functions of in vitro-generated simian virus 40 large T antigen mutants.

We used sodium bisulfite mutagenesis to introduce point mutations within the early region of the simian virus 40 genome. Seventeen mutants which contained amino acid changes in the amino-terminal half of the large T antigen coding sequence were assayed for their ability to replicate viral DNA and to...

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Hlavní autoři: Rutila, J E, Imperiale, M J, Brockman, W W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC252941/
https://ncbi.nlm.nih.gov/pubmed/3009866
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