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Protection of Retinal Cells from Ischemia by a Novel Gap Junction Inhibitor
Retinal cells which become ischemic will pass apoptotic signal to adjacent cells, resulting in the spread of damage. This occurs through open gap junctions. A class of novel drugs, based on primaquine (PQ), was tested for binding to connexin 43 using simulated docking studies. A novel drug has been...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529171/ https://ncbi.nlm.nih.gov/pubmed/18590704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.06.069 |
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