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Protection from Ataxia-linked Apoptosis by Gap Junction Inhibitors

Mutations in the protein kinase C γ (PKCγ) gene cause spinocerebellar ataxia type 14 (SCA14), a heterogeneous neurodegenerative disorder. Synthetic peptides (C1B1) serve as gap junction inhibitors through activation of PKCγ control of gap junctions. We investigated the neuroprotective potential of t...

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Autori principali: Lin, Dingbo, Takemoto, Dolores J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034346/
https://ncbi.nlm.nih.gov/pubmed/17822669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.093
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