Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase

The replication terminator protein Tus of Escherichia coli promotes polar fork arrest at sequence-specific replication termini (Ter) by antagonizing DNA unwinding by the replicative helicase DnaB. Here, we report that Tus is also a polar antitranslocase. We have used this activity as a tool to uncou...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bastia, Deepak, Zzaman, Shamsu, Krings, Gregor, Saxena, Mukesh, Peng, Xiaohua, Greenberg, Marc M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529109/
https://ncbi.nlm.nih.gov/pubmed/18708526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805898105
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky