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Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase
The replication terminator protein Tus of Escherichia coli promotes polar fork arrest at sequence-specific replication termini (Ter) by antagonizing DNA unwinding by the replicative helicase DnaB. Here, we report that Tus is also a polar antitranslocase. We have used this activity as a tool to uncou...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529109/ https://ncbi.nlm.nih.gov/pubmed/18708526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805898105 |
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