Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma

Neuroblastoma accounts for nearly 15% of all pediatric cancer-related deaths. We have previously shown that gastrin-releasing peptide (GRP) stimulates neuroblastoma growth, and that its cell surface receptor, GRP-R, is overexpressed in advanced-stage human neuroblastomas; however, the effects of GRP...

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Bibliografske podrobnosti
Main Authors: Qiao, Jingbo, Kang, JungHee, Ishola, Titilope A., Rychahou, Piotr G., Evers, B. Mark, Chung, Dai H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529092/
https://ncbi.nlm.nih.gov/pubmed/18753628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711861105
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