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Phosphatidylinositol 3-Kinase Regulation of Gastrin-Releasing Peptide-Induced Cell Cycle Progression in Neuroblastoma Cells
Gastrin-releasing peptide (GRP), the mammalian equivalent of bombesin (BBS), is an autocrine growth factor for neuroblastoma; its receptor is up-regulated in undifferentiated neuroblastomas. The phosphatidylinositol 3-kinase (PI3K) is a critical cell survival pathway; it is negatively regulated by t...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708969/ https://ncbi.nlm.nih.gov/pubmed/17379415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2007.02.002 |
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