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Targeting Gastrin-Releasing Peptide as a New Approach to Treat Aggressive Refractory Neuroblastomas

BACKGROUND: The overall survival for neuroblastoma remains dismal, largely in part, due to emergence of resistance to chemotherapeutic drugs. We have demonstrated that gastrin-releasing peptide (GRP), a gut peptide secreted by neuroblastoma, act as an autocrine growth factor. We hypothesized that kn...

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Autori principali: Paul, Pritha, Gillory, Lauren A., Kang, JungHee, Qiao, Jingbo, Chung, Dai H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668794/
https://ncbi.nlm.nih.gov/pubmed/21035156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.08.011
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