HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility

The major locus for multiple sclerosis (MS) susceptibility is located within the class II region of the Major Histocompatibility Complex (MHC). HLA-DRB1 alleles, constituting the strongest MS susceptibility factors, have been widely exploited in research including construction of transgenic animal m...

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Hlavní autoři: Chao, Michael J., Barnardo, Martin C. N. M., Lincoln, Matthew R., Ramagopalan, Sreeram V., Herrera, Blanca M., Dyment, David A., Montpetit, Alexandre, Sadovnick, A. Dessa, Knight, Julian C., Ebers, George C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529028/
https://ncbi.nlm.nih.gov/pubmed/18765817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801042105
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