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Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones
The epothilones represent a promising class of natural product-based antitumor drug candidates. Although these compounds operate through a microtubule stabilization mechanism similar to that of taxol, the epothilones offer a major potential therapeutic advantage in that they retain their activity ag...
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| Hoofdauteurs: | , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529025/ https://ncbi.nlm.nih.gov/pubmed/18755900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804773105 |
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