His-311 and Arg-559 Are Key Residues Involved in Fatty Acid Oxygenation in Pathogen-inducible Oxygenase

Pathogen-inducible oxygenase (PIOX) oxygenates fatty acids into 2R-hydroperoxides. PIOX belongs to the fatty acid α-dioxygenase family, which exhibits homology to cyclooxygenase enzymes (COX-1 and COX-2). Although these enzymes share common catalytic features, including the use of a tyrosine radical...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Koszelak-Rosenblum, Mary, Krol, Adam C., Simmons, Danielle M., Goulah, Christopher C., Wroblewski, Liliana, Malkowski, Michael G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2008
Θέματα:
Enzyme Catalysis and Regulation
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529013/
https://ncbi.nlm.nih.gov/pubmed/18596034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804358200
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