Identification of Novel Endogenous Cytochrome P450 Arachidonate Metabolites with High Affinity for Cannabinoid Receptors

Arachidonic acid is an essential constituent of cell membranes that is esterified to the sn-2-position of glycerophospholipids and is released from selected lipid pools by phospholipase cleavage. The released arachidonic acid can be metabolized by three enzymatic pathways: the cyclooxygenase pathway...

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Main Authors: Chen, Jian-Kang, Chen, Jianchun, Imig, John D., Wei, Shouzuo, Hachey, David L., Guthi, Jagadeesh Setti, Falck, John R., Capdevila, Jorge H., Harris, Raymond C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528993/
https://ncbi.nlm.nih.gov/pubmed/18606824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709873200
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