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Processing of G4 DNA by Dna2 Helicase/Nuclease and Replication Protein A (RPA) Provides Insights into the Mechanism of Dna2/RPA Substrate Recognition

The polyguanine-rich DNA sequences commonly found at telomeres and in rDNA arrays have been shown to assemble into structures known as G quadruplexes, or G4 DNA, stabilized by base-stacked G quartets, an arrangement of four hydrogen-bonded guanines. G4 DNA structures are resistant to the many helica...

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Autores principales: Masuda-Sasa, Taro, Polaczek, Piotr, Peng, Xiao P., Chen, Lu, Campbell, Judith L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528986/
https://ncbi.nlm.nih.gov/pubmed/18593712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802244200
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