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An Adamantyl-Substituted Retinoid-Derived Molecule That Inhibits Cancer Cell Growth and Angiogenesis by Inducing Apoptosis and Binds to Small Heterodimer Partner Nuclear Receptor: Effects of Modifying Its Carboxylate Group on Apoptosis, Proliferation, and Protein-Tyrosine Phosphatase Activity

Apoptotic and antiproliferative activities of small heterodimer partner (SHP) nuclear receptor ligand (E)-4-[3′-(1-adamantyl)-4′-hydroxyphenyl]-3-chlorocinnamic acid (3-Cl-AHPC), which was derived from 6-[3′-(1-adamantyl)-4′-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN), and several carboxyl is...

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Detalhes bibliográficos
Main Authors: Dawson, Marcia I., Xia, Zebin, Liu, Gang, Ye, Mao, Fontana, Joseph A., Farhana, Lulu, Patel, Bhamik B., Arumugarajah, Sankari, Bhuiyan, Mohammad, Zhang, Xiao-Kun, Han, Young-Hoon, Stallcup, William B., Fukushi, Jun-ichi, Mustelin, Tomas, Tautz, Lutz, Su, Ying, Harris, Danni L., Waleh, Nahid, Hobbs, Peter D., Jong, Ling, Chao, Wan-ru, Schiff, Leonard J., Sani, Brahma P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528874/
https://ncbi.nlm.nih.gov/pubmed/17489579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0613323
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