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Benzodiazepine ligands can act as allosteric modulators of the Type 1 cholecystokinin receptor
The cholecystokinin (CCK(1)) receptor is a G protein-coupled receptor important for nutrient homeostasis. The molecular basis of CCK-receptor binding has been debated, with one prominent model suggesting occupation of the same region of the intramembranous helical bundle as benzodiazepines. Here, we...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2528863/ https://ncbi.nlm.nih.gov/pubmed/18621527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.06.053 |
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