A high-throughput percentage-of-binding strategy to measure binding energies in DNA–protein interactions: application to genome-scale site discovery

Quantifying the binding energy in DNA–protein interactions is of critical importance to understand transcriptional regulation. Based on a simple computational model, this study describes a high-throughput percentage-of-binding strategy to measure the binding energy in DNA–protein interactions betwee...

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Autores principales: Wang, Xiaohu, Gao, Haichun, Shen, Yufeng, Weinstock, George M., Zhou, Jizhong, Palzkill, Timothy
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528174/
https://ncbi.nlm.nih.gov/pubmed/18653527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn477
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