Specific and Efficient Binding of XPA to Double-strand/Single-strand DNA Junctions with 3′- and/or 5′-ssDNA Branches

Human XPA is an important DNA damage recognition protein in nucleotide excision repair (NER). We previously observed that XPA binds to DNA lesion as a homodimer (1). Herein we report that XPA recognized undamaged DNA doublestrand/ single-strand (ds-ssDNA) junctions containing ssDNA branches with bin...

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Bibliografiske detaljer
Main Authors: Yang, Zhengguan, Roginskaya, Marina, Colis, Laureen C., Basu, Ashis K., Shell, Steven M., Liu, Yiyong, Musich, Phillip R., Harris, Constance M., Harris, Thomas M., Zou, Yue
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528077/
https://ncbi.nlm.nih.gov/pubmed/17176115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061626q
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