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Cooperative Interaction of Human XPA Stabilizes and Enhances Specific Binding of XPA to DNA Damage

Human xeroderma pigmentosum group A (XPA) is an essential protein for nucleotide excision repair (NER). We have previously reported that XPA forms a homodimer in the absence of DNA. However, what oligomeric forms of XPA are involved in DNA damage recognition and how the interaction occurs in terms o...

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Detalhes bibliográficos
Main Authors: Liu, Yu, Liu, Yiyong, Yang, Zhengguan, Wang, Guizhi, Zou, Yue, Utzat, Christopher, Basu, Ashis K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475732/
https://ncbi.nlm.nih.gov/pubmed/15882075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi047598y
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