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A Structural Characterization of Human RPA Sequential Binding to Single-Stranded DNA Using ssDNA as a Molecular Ruler

Human replication protein A (RPA), a heterotrimer composed of RPA70, RPA32, and RPA14 subunits, contains four single-stranded DNA (ssDNA) binding domains (DBD): DBD-A, DBD-B and DBD-C in RPA70 and DBD-D in RPA32. While crystallographic or NMR structures of these DBDs and a trimerization core have be...

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Detalhes bibliográficos
Main Authors: Cai, Lifeng, Roginskaya, Marina, Qu, Youxing, Yang, Zhengguan, Xu, Ying, Zou, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553558/
https://ncbi.nlm.nih.gov/pubmed/17583916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7004976
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