Mechanoenzymatics of titin kinase

Biological responses to mechanical stress require strain-sensing molecules, whose mechanically induced conformational changes are relayed to signaling cascades mediating changes in cell and tissue properties. In vertebrate muscle, the giant elastic protein titin is involved in strain sensing via its...

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Hlavní autoři: Puchner, Elias M., Alexandrovich, Alexander, Kho, Ay Lin, Hensen, Ulf, Schäfer, Lars V., Brandmeier, Birgit, Gräter, Frauke, Grubmüller, Helmut, Gaub, Hermann E., Gautel, Mathias
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527993/
https://ncbi.nlm.nih.gov/pubmed/18765796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805034105
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