Mechanoenzymatics of titin kinase

Biological responses to mechanical stress require strain-sensing molecules, whose mechanically induced conformational changes are relayed to signaling cascades mediating changes in cell and tissue properties. In vertebrate muscle, the giant elastic protein titin is involved in strain sensing via its...

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Bibliografiske detaljer
Main Authors: Puchner, Elias M., Alexandrovich, Alexander, Kho, Ay Lin, Hensen, Ulf, Schäfer, Lars V., Brandmeier, Birgit, Gräter, Frauke, Grubmüller, Helmut, Gaub, Hermann E., Gautel, Mathias
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527993/
https://ncbi.nlm.nih.gov/pubmed/18765796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805034105
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