Mechanoenzymatics of titin kinase

Biological responses to mechanical stress require strain-sensing molecules, whose mechanically induced conformational changes are relayed to signaling cascades mediating changes in cell and tissue properties. In vertebrate muscle, the giant elastic protein titin is involved in strain sensing via its...

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Autori principali: Puchner, Elias M., Alexandrovich, Alexander, Kho, Ay Lin, Hensen, Ulf, Schäfer, Lars V., Brandmeier, Birgit, Gräter, Frauke, Grubmüller, Helmut, Gaub, Hermann E., Gautel, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527993/
https://ncbi.nlm.nih.gov/pubmed/18765796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805034105
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