Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB(1) receptor

BACKGROUND AND PURPOSE: Long-term adaptations to pharmacological stimuli frequently originate from modulation of complex intracellular signalling pathways. We previously reported that HU210 and CP55940, two CB(1) cannabinoid receptor agonists, induced opposite effects on TH expression. Herein, we ch...

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Detalles Bibliográficos
Main Authors: Bosier, B, Hermans, E, Lambert, D M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527844/
https://ncbi.nlm.nih.gov/pubmed/18536748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.230
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