Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB(1) receptor

BACKGROUND AND PURPOSE: Long-term adaptations to pharmacological stimuli frequently originate from modulation of complex intracellular signalling pathways. We previously reported that HU210 and CP55940, two CB(1) cannabinoid receptor agonists, induced opposite effects on TH expression. Herein, we ch...

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Bibliografiska uppgifter
Huvudupphovsmän: Bosier, B, Hermans, E, Lambert, D M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2008
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527844/
https://ncbi.nlm.nih.gov/pubmed/18536748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.230
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