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Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB(1) receptor
BACKGROUND AND PURPOSE: Long-term adaptations to pharmacological stimuli frequently originate from modulation of complex intracellular signalling pathways. We previously reported that HU210 and CP55940, two CB(1) cannabinoid receptor agonists, induced opposite effects on TH expression. Herein, we ch...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527844/ https://ncbi.nlm.nih.gov/pubmed/18536748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.230 |
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