Variant influenza virus hemagglutinin that induces fusion at elevated pH.

The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion of the virion with intracellular membranes, liberating the genome into the cytoplasm. The pH dependen...

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Bibliographic Details
Main Authors: Doms, R W, Gething, M J, Henneberry, J, White, J, Helenius, A
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC252775/
https://ncbi.nlm.nih.gov/pubmed/3003392
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