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Variant influenza virus hemagglutinin that induces fusion at elevated pH.

The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion of the virion with intracellular membranes, liberating the genome into the cytoplasm. The pH dependen...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Doms, R W, Gething, M J, Henneberry, J, White, J, Helenius, A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.2.603-613.1986
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