Variant influenza virus hemagglutinin that induces fusion at elevated pH.
The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion of the virion with intracellular membranes, liberating the genome into the cytoplasm. The pH dependen...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1986
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003392/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.2.603-613.1986 |
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