Cargando...

Broad expression of the FoxP3 locus in epithelial cells: A caution against an early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells

Dogma that the Treg prevents catastrophic autoimmunity throughout the lifespan relies on the assumption that the FoxP3 locus is transcribed exclusively in Treg. To test the assumption, we used the Rag2(−/−) and the Rag2(−/−) mice with the Scurfy mutation (FoxP3(sf/y) or FoxP3(sf/sf)) to evaluate Fox...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Chen, Guo-Yun, Chen, Chong, Wang, Lizhong, Chang, Xing, Zheng, Pan, Liu, Yang
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527697/
https://ncbi.nlm.nih.gov/pubmed/18390696
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!