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Kinetics of CO Insertion and Acetyl Group Transfer Steps, and a Model of the Acetyl-CoA Synthase Catalytic Mechanism

Acetyl-CoA synthase/carbon monoxide dehydrogenase is a Ni-Fe-S-containing enzyme that catalyzes the synthesis of acetyl-CoA from CO, CoA and a methyl group. The methyl group is transferred onto the enzyme from a corrinoid-iron-sulfur protein (CoFeSP). The kinetics of two steps within the catalytic m...

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Detalhes bibliográficos
Main Authors: Tan, Xiangshi, Surovtsev, Ivan V., Lindahl, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527582/
https://ncbi.nlm.nih.gov/pubmed/16967985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0627702
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