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Nanomechanical Properties of Human Prion Protein Amyloid as Probed by Force Spectroscopy
Amyloids are associated with a number of protein misfolding disorders, including prion diseases. In this study, we used single-molecule force spectroscopy to characterize the nanomechanical properties and molecular structure of amyloid fibrils formed by human prion protein PrP90-231. Force-extension...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527243/ https://ncbi.nlm.nih.gov/pubmed/18539633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133108 |
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