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Seizure responses and induction of Fos by the NMDA Agonist (tetrazol-5-yl)glycine in a genetic model of NMDA receptor hypofunction

Effects of the direct NMDA agonist (tetrazol-5-yl)glycine (TZG) were examined in a genetic mouse model of reduced NMDA receptor function. In this model, expression of the NR1 subunit is reduced but not eliminated and the mice are therefore designated as NR1 hypomorphic. Previous work suggested that...

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Detalhes bibliográficos
Main Authors: Duncan, Gary E., Inada, Ken, Farrington, Joseph S., Koller, Beverly H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527124/
https://ncbi.nlm.nih.gov/pubmed/18550035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.05.001
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