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An Antimetastatic Role for Decorin in Breast Cancer

Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase family and attenuates their signaling, leading to growth inhibition. We investigated the effects of decorin on the growth of ErbB2-overexpressing mammary carcinoma cells...

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Autors principals: Goldoni, Silvia, Seidler, Daniela G., Heath, Jack, Fassan, Matteo, Baffa, Raffaele, Thakur, Mathew L., Owens, Rick T., McQuillan, David J., Iozzo, Renato V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527080/
https://ncbi.nlm.nih.gov/pubmed/18688028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080275
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