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Involvement of ATP-dependent Pseudomonas Exotoxin Translocation from a Late Recycling Compartment in Lymphocyte Intoxication Procedure

Pseudomonas exotoxin (PE) is a cytotoxin which, after endocytosis, is delivered to the cytosol where it inactivates protein synthesis. Using diaminobenzidine cytochemistry, we found over 94% of internalized PE in transferrin (Tf) -positive endosomes of lymphocytes. When PE translocation was examined...

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Main Authors: Alami, Mériem, Taupiac, Marie-Pierre, Reggio, Hubert, Bienvenüe, Alain, Beaumelle, Bruno
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 1998
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC25269/
https://ncbi.nlm.nih.gov/pubmed/9450963
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