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Dual Localization of Squalene Epoxidase, Erg1p, in Yeast Reflects a Relationship between the Endoplasmic Reticulum and Lipid Particles

Squalene epoxidase, encoded by the ERG1 gene in yeast, is a key enzyme of sterol biosynthesis. Analysis of subcellular fractions revealed that squalene epoxidase was present in the microsomal fraction (30,000 × g) and also cofractionated with lipid particles. A dual localization of Erg1p was confirm...

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Autori principali: Leber, Regina, Landl, Karina, Zinser, Erwin, Ahorn, Horst, Spök, Armin, Kohlwein, Sepp D., Turnowsky, Friederike, Daum, Günther
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25265/
https://ncbi.nlm.nih.gov/pubmed/9450962
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