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A Novel Lumazine Synthase Inhibitor Derived from Oxidation of 1,3,6,8-Tetrahydroxy-2,7-naphthyridine to a Tetraazaperylenehexaone Derivative

Air oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine afforded 2,5,8,11-tetraaza-5,11-dihydro-4,10-dihydroxyperylene-1,3,6,7,9,12-hexaone. X-Ray crystallography of the product revealed that it exists in the meso form in the solid state. The mechanism of product formation most likely involves oxida...

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Autors principals: Zhang, Yanlei, Illarionov, Boris, Bacher, Adelbert, Fischer, Markus, Georg, Gunda I., Ye, Qi-Zhuang, Velde, David Vander, Fanwick, Phillip E., Song, Yunlong, Cushman, Mark
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526313/
https://ncbi.nlm.nih.gov/pubmed/17348709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo062246d
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