The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis

The nuclear factor of activated T cells (NFAT) family of transcription factors controls calcium signaling in T lymphocytes. In this study, we have identified a crucial regulatory role of the transcription factor NFATc2 in T cell–dependent experimental colitis. Similar to ulcerative colitis in humans...

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Hlavní autoři: Weigmann, Benno, Lehr, Hans A., Yancopoulos, George, Valenzuela, David, Murphy, Andrew, Stevens, Sean, Schmidt, Jan, Galle, Peter R., Rose-John, Stefan, Neurath, Markus F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526204/
https://ncbi.nlm.nih.gov/pubmed/18710929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072484
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