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Role of the IL-2 inducible tyrosine kinase ITK and its inhibitors in disease pathogenesis
ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines. Studie...
Tallennettuna:
| Julkaisussa: | J Mol Med (Berl) |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Springer Berlin Heidelberg
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7524833/ https://ncbi.nlm.nih.gov/pubmed/32808093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01958-z |
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