The transcription factor IFN regulatory factor–4 controls experimental colitis in mice via T cell–derived IL-6

The proinflammatory cytokine IL-6 seems to have an important role in the intestinal inflammation that characterizes inflammatory bowel diseases (IBDs) such as Crohn disease and ulcerative colitis. However, little is known about the molecular mechanisms regulating IL-6 production in IBD. Here, we ass...

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Main Authors: Mudter, Jonas, Amoussina, Lioubov, Schenk, Mirjam, Yu, Jingling, Brüstle, Anne, Weigmann, Benno, Atreya, Raja, Wirtz, Stefan, Becker, Christoph, Hoffman, Arthur, Atreya, Imke, Biesterfeld, Stefan, Galle, Peter R., Lehr, Hans A., Rose-John, Stefan, Mueller, Christoph, Lohoff, Michael, Neurath, Markus F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413182/
https://ncbi.nlm.nih.gov/pubmed/18535667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33227
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