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Elevations of Endogenous Kynurenic Acid Produce Spatial Working Memory Deficits

Kynurenic acid (KYNA) is a tryptophan metabolite that is synthesized and released by astrocytes and acts as a competitive antagonist of the glycine site of N-methyl-D-aspartate receptors at high concentrations and as a noncompetitive antagonist of the α7-nicotinic acetylcholine receptor at low conce...

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Detalhes bibliográficos
Main Authors: Chess, Amy C., Simoni, Michael K., Alling, Torey E., Bucci, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526148/
https://ncbi.nlm.nih.gov/pubmed/16920787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbl033
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