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Elevations of Endogenous Kynurenic Acid Produce Spatial Working Memory Deficits
Kynurenic acid (KYNA) is a tryptophan metabolite that is synthesized and released by astrocytes and acts as a competitive antagonist of the glycine site of N-methyl-D-aspartate receptors at high concentrations and as a noncompetitive antagonist of the α7-nicotinic acetylcholine receptor at low conce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526148/ https://ncbi.nlm.nih.gov/pubmed/16920787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbl033 |
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