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14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 in Xenopus Egg Extracts

Cdc25, the dual-specificity phosphatase that dephosphorylates the Cdc2–cyclin B complex at mitosis, is highly regulated during the cell cycle. In Xenopus egg extracts, Cdc25 is associated with two isoforms of the 14-3-3 protein. Cdc25 is complexed primarily with 14-3-3ε and to a lesser extent with 1...

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Detaylı Bibliyografya
Asıl Yazarlar: Kumagai, Akiko, Yakowec, Peter S., Dunphy, William G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC25261/
https://ncbi.nlm.nih.gov/pubmed/9450960
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