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14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 in Xenopus Egg Extracts

Cdc25, the dual-specificity phosphatase that dephosphorylates the Cdc2–cyclin B complex at mitosis, is highly regulated during the cell cycle. In Xenopus egg extracts, Cdc25 is associated with two isoforms of the 14-3-3 protein. Cdc25 is complexed primarily with 14-3-3ε and to a lesser extent with 1...

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書目詳細資料
Main Authors: Kumagai, Akiko, Yakowec, Peter S., Dunphy, William G.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC25261/
https://ncbi.nlm.nih.gov/pubmed/9450960
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