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Mammalian Rrn3 Is Required for the Formation of a Transcription Competent Preinitiation Complex Containing RNA Polymerase I

Mammalian Rrn3, an essential, polymerase-associated protein, is inactivated when cells are treated with cycloheximide, resulting in the inhibition of transcription by RNA polymerase I. Although Rrn3 is essential for transcription, its function in rDNA transcription has not been determined. For examp...

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Bibliografiske detaljer
Main Authors: Cavanaugh, Alice H., Evans, Ann, Rothblum, Lawrence I.
Format: Artigo
Sprog:Inglês
Udgivet: Cognizant Communication Corporation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526047/
https://ncbi.nlm.nih.gov/pubmed/18590050
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