Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast

Three Upf proteins are essential to the nonsense-mediated mRNA decay (NMD) pathway. Although these proteins assemble on polysomes for recognition of aberrant mRNAs containing premature termination codons, the significance of this assembly remains to be elucidated. The Cys- and His-rich repeated N te...

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Auteurs principaux: Takahashi, Shinya, Araki, Yasuhiro, Ohya, Yuriko, Sakuno, Takeshi, Hoshino, Shin-Ichi, Kontani, Kenji, Nishina, Hiroshi, Katada, Toshiaki
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525956/
https://ncbi.nlm.nih.gov/pubmed/18676617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.536308
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