Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast

Three Upf proteins are essential to the nonsense-mediated mRNA decay (NMD) pathway. Although these proteins assemble on polysomes for recognition of aberrant mRNAs containing premature termination codons, the significance of this assembly remains to be elucidated. The Cys- and His-rich repeated N te...

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Main Authors: Takahashi, Shinya, Araki, Yasuhiro, Ohya, Yuriko, Sakuno, Takeshi, Hoshino, Shin-Ichi, Kontani, Kenji, Nishina, Hiroshi, Katada, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525956/
https://ncbi.nlm.nih.gov/pubmed/18676617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.536308
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