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Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast
Three Upf proteins are essential to the nonsense-mediated mRNA decay (NMD) pathway. Although these proteins assemble on polysomes for recognition of aberrant mRNAs containing premature termination codons, the significance of this assembly remains to be elucidated. The Cys- and His-rich repeated N te...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525956/ https://ncbi.nlm.nih.gov/pubmed/18676617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.536308 |
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