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Interaction between Ski7p and Upf1p is required for nonsense-mediated 3′-to-5′ mRNA decay in yeast
Aberrant mRNAs containing premature termination codons (PTC-mRNAs) are degraded by a conserved surveillance system, referred to as the nonsense- mediated decay (NMD) pathway. Although NMD is reported to operate on the decapping and 5′-to-3′ exonucleolytic decay of PTC-mRNAs without affecting deadeny...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169047/ https://ncbi.nlm.nih.gov/pubmed/12881429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg374 |
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