Immune-driven recombination and loss of control after HIV superinfection

After acute HIV infection, CD8(+) T cells are able to control viral replication to a set point. This control is often lost after superinfection, although the mechanism behind this remains unclear. In this study, we illustrate in an HLA-B27(+) subject that loss of viral control after HIV superinfecti...

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Autori principali: Streeck, Hendrik, Li, Bin, Poon, Art F.Y., Schneidewind, Arne, Gladden, Adrianne D., Power, Karen A., Daskalakis, Demetre, Bazner, Suzane, Zuniga, Rosario, Brander, Christian, Rosenberg, Eric S., Frost, Simon D.W., Altfeld, Marcus, Allen, Todd M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2008
Soggetti:
Brief Definitive Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525594/
https://ncbi.nlm.nih.gov/pubmed/18625749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080281
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