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Rapid mass spectrometric analysis of (15)N-Leu incorporation fidelity during preparation of specifically labeled NMR samples
Advances in NMR spectroscopy have enabled the study of larger proteins that typically have significant overlap in their spectra. Specific (15)N-amino acid incorporation is a powerful tool for reducing spectral overlap and attaining reliable sequential assignments. However, scrambling of the label du...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525515/ https://ncbi.nlm.nih.gov/pubmed/18567787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.036418.108 |
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